DTPA+
Kit for the Preparation of Technetium Tc 99m Pentetate Injection
DIAGNOSTIC
For Intravenous Use
DESCRIPTION
The kit consists of reaction vials which contain the sterile, nonpyrogenic, non-radioactive ingredients necessary to produce Technetium Tc 99m Pentetate Injection for diagnostic use by intravenous injection or for inhalation after nebulization to a radio-aerosol. Each 10 mL reaction vial contains 20.0 mg of pentetic acid, 3.73 mg of calcium chloride dihydrate, 0.35 mg stannous chloride dihydrate, and 5.0 mg of p-aminobenzoic acid in lyophilized form under an atmosphere of nitrogen. Sodium hydroxide and/or hydrochloric acid has been used for pH adjustment. The pH of the reconstituted radiopharmaceutical is 6.5 to 7.5. The addition of sterile, non-pyrogenic, and oxidant-free sodium pertechnetate Tc 99m solution produces a rapid labelling which is essentially quantitative and which remains stable in vitro throughout the 12-hour life of the preparation. No bacteriostatic preservative is present. The structure of the chelate is: Its